Xin He

Principal Investigator

Xin completed his PhD in Computer Science in 2009 at University of Illinois at Urbana-Champaign, where he worked with Saurabh Sinha. Before his current position, Xin completed postdoc training with Dr. Hao Li at Department of Biochemistry of UCSF, and with Drs. Kathryn Roeder and Ziv Bar-Joseph at Lane Center for Computational Biology of Carnegie Mellon University. Xin is interested in statistical genetics and genomics, computational biology/bioinformatics and evolutionary genomics.


Kevin Luo


Kevin (Kaixuan罗凯旋) Luo completed his PhD in Computational Biology and Bioinformatics in 2016 from Duke University, where he was supervised by Dr. Alex Hartemink, and collaborated with Greg Crawford, David MacAlpine, and Li Ma. His PhD research focused on modeling the dynamics of genome-wide transcription factor and nucleosome occupancy. Kevin joined the lab in October, 2016. He is jointly supervised by Dr. Matthew Stephens, and in close collaboration with Dr. Chuan He. Kevin is interested in developing statistical and machine learning methods to better understand the mechanisms by which genetic variation impacts gene regulation.


Jean Morrison


Jean Morrison recieved her Ph.D. in 2016 in Biostatistics from the University of Washington advised by Noah Simon. Jean joined the lab in Oct, 2016 and is co-supervised by Dr. Matthew Stephens. She is particularly excited about understanding the genetic architecture of gene regulation, integrating multiple genetic studies to learn about the biological relationships between traits, and association testing with spatially structured data types.


Siming Zhao


Siming Zhao receieved her Ph.D. in 2015 in Genetics from Yale University advised by Dr. Richard Lifton. Siming joined the lab in Oct, 2015 and is co-supervised by Dr. Matthew Stephens. She is interested in cancer genomics and applying statistical methods to understand the genetic basis of human diseases.


Nicholas Knoblauch

PhD student

Nick obtained his BS in Biochemistry and Molecular Biology from UC Davis in 2011, and worked at Harvard Medical School as a Research Assistant afterwards. Nick joined the Genetics, Genomics and Systems Biology (GGSB) program at U of Chicago as a PhD student in 2014. His research interest is the application of machine learning and statistical methods to large scale genotypic and phenotypic datasets to better understand the mechanisms of human disesase.


Alan Selewa

PhD student

Alan received his BS in Physics from the University of Illinois in Urbana-Champaign and joined the PhD program in Biophysical Sciences at the University of Chicago in 2016. He joined the lab in September, 2017 and is jointly supervised by Dr. Oni Basu. He is interested in developing statistical methods for analyzing single-cell ‘omics data in order to study cell-to-cell variability and its role in human disease.


Yifan Zhou

PhD student

Yifan Zhou (周逸凡) obtained her BS in Chemistry and Biology from Tsinghua University in China and joined the PhD program in Biophysical Sciences at University of Chicago in 2016. She joined the lab in August, 2017 and is jointly supervised by Dr. Mengjie Chen. Yifan is interested in using statistical methods on large scale gene datasets to better understand the architecture and mechanisms of gene regulation, as well as to identify disease related non-coding elements.



Sheng Qian

Research assistant

Sheng Qian obtained his BS in Biometry & Statistics from Cornell University and in Applied Bioscience from Zhejiang University jointly in 2019. He joined the lab in July, 2019 as a research assistant. He is interested in the development and application of machine learning approaches in precision medicine.


Zhongshan Li

Visiting scholar

Zhongshan Li (李中山) obtained his Ph.D degree in computational biology in 2013 from CAS-MPG Partner Institute for Computational Biology. After that, he works in the Institute of Genomic Medicine, Wenzhou Medical University. He came to the lab in Sep, 2017 as a visiting scholar. Zhongshan’s research interest mainly focus on identification of pathogenic genetic mutations for human neuropsychiatric disorders using bioinformatics and statistics methods.


Min Qiao

Visiting student

Min is a visiting PhD student from UTHealth at Houston. She received her MS in Biostatistics from UTHealth in 2014 and joined Dr. He's lab in April 2019. Her research interest is developing and applying statistical methods for identifying functional genes and variants for psychiatric disorders.



Yubin Xie 

Research Assistant

Yubin Xie was a research assistant in the lab from October, 2016 to June, 2017. He is now a PhD student at Tri-Institutional PhD Program in Computational Biology & Medicine.


Tiffany Ke

Visiting student

Tiffany, Xinxin KE (柯欣欣) was a visiting student from School of Life Sciences, The Chinese University of Hong Kong. She visited the lab from Oct, 2017 to Mar, 2018.


Yuwen Liu


Yuwen (刘毓文)  was a postdoc in the lab from July, 2015 to Jul, 2018. He is now a PI at Agricultural Genome Institute at Shenzhen, Chinese Academy of Agricultural Sciences.


Shengtong Han


Shengtong Han was a postdoc in the lab from Apr, 2015 to Aug, 2018. He is now a  Visiting Assistant Professor in Biostatistics in Joseph J. Zilber School of Public Health, University of Wisconsin, Milwaukee.

Yanyu Liang

Research assistant

Yanyu Liang was a Research Assistant in the lab from 2016 to 2017. She did a rotation in the lab in the spring of 2018. She is now a student at Genomics and Systems Biology (GGSB) program, working in the lab of Haky Im.