Xin He

Principal Investigator

Xin completed his PhD in Computer Science in 2009 at University of Illinois at Urbana-Champaign, where he worked with Saurabh Sinha. Before his current position, Xin completed postdoc training with Dr. Hao Li at Department of Biochemistry of UCSF, and with Drs. Kathryn Roeder and Ziv Bar-Joseph at Lane Center for Computational Biology of Carnegie Mellon University. Xin is interested in statistical genetics and genomics, computational biology/bioinformatics and evolutionary genomics.


Shengtong Han


Shengtong (韩圣同) obtained his Ph.D. degree in Statistics in 2012 from the Department of Statistics, the Chinese University of Hong Kong. After that, Shengtong did postdoc research work at Department of Epidemiology and Biostatistics at the University of South Carolina, Columbia. He joined the lab in April, 2015. Shengtong's research interests include Bayesian networks, semi-parametric methods and their application in statistical genetics/genomics.


Yuwen Liu


Yuwen (刘毓文) obtained his Ph.D. in Developmental Biology (Specialized in Genomics and Systems Biology) from University of Chicago in 2014. Under the supervision of Dr. Kevin White, he has trainings in both experimental and computational genomics. He joined the lab in June, 2015. Yuwen’s research interests include developing statistical and computational methods to integrate various types of biological dataset to identify disease-causing DNA variants and pathways.


Kevin Luo


Kevin (Kaixuan罗凯旋) Luo completed his PhD in Computational Biology and Bioinformatics in 2016 from Duke University, where he was supervised by Dr. Alex Hartemink, and collaborated with Greg Crawford, David MacAlpine, and Li Ma. His PhD research focused on modeling the dynamics of genome-wide transcription factor and nucleosome occupancy. Kevin joined the lab in October, 2016. He is jointly supervised by Dr. Matthew Stephens, and in close collaboration with Dr. Chuan He. Kevin is interested in developing statistical and machine learning methods to better understand the mechanisms by which genetic variation impacts gene regulation.


Jean Morrison


Jean Morrison recieved her Ph.D. in 2016 in Biostatistics from the University of Washington advised by Noah Simon. Jean joined the lab in Oct, 2016 and is co-supervised by Dr. Matthew Stephens. She is particularly excited about understanding the genetic architecture of gene regulation, integrating multiple genetic studies to learn about the biological relationships between traits, and association testing with spatially structured data types.


Siming Zhao


Siming Zhao receieved her Ph.D. in 2015 in Genetics from Yale University advised by Dr. Richard Lifton. Siming joined the lab in Oct, 2015 and is co-supervised by Dr. Matthew Stephens. She is interested in cancer genomics and applying statistical methods to understand the genetic basis of human diseases.


Nicholas Knoblauch

PhD student

Nick obtained his BS in Biochemistry and Molecular Biology from UC Davis in 2011, and worked at Harvard Medical School as a Research Assistant afterwards. Nick joined the Genetics, Genomics and Systems Biology (GGSB) program at U of Chicago as a PhD student in 2014. His research interest is the application of machine learning and statistical methods to large scale genotypic and phenotypic datasets to better understand the mechanisms of human disesase.


Alan Selewa

PhD student

Alan received his BS in Physics from the University of Illinois in Urbana-Champaign and joined the PhD program in Biophysical Sciences at the University of Chicago in 2016. He joined the lab in September, 2017 and is jointly supervised by Dr. Oni Basu. He is interested in developing statistical methods for analyzing single-cell ‘omics data in order to study cell-to-cell variability and its role in human disease.


Yifan Zhou

PhD student

Yifan Zhou (周逸凡) obtained her BS in Chemistry and Biology from Tsinghua University in China and joined the PhD program in Biophysical Sciences at University of Chicago in 2016. She joined the lab in August, 2017 and is jointly supervised by Dr. Mengjie Chen. Yifan is interested in using statistical methods on large scale gene datasets to better understand the architecture and mechanisms of gene regulation, as well as to identify disease related non-coding elements.

Yanyu Liang

Research assistant

Yanyu obtained BSc in Chemical Biology from Tsinghua University in China in 2015, and she completed MSc in Computational Biology from Carnegie Mellon University in 2016. She is currently a student in Genetics, Genomics and Systems Biology (GGSB) program. Her research interest is to understand the disease mechanisms from multi-level NGS data with the use of machine learning techniques and statistical modeling.


Zhongshan Li

Visiting scholar

Zhongshan Li (李中山) obtained his Ph.D degree in computational biology in 2013 from CAS-MPG Partner Institute for Computational Biology. After that, he works in the Institute of Genomic Medicine, Wenzhou Medical University. He came to the lab in Sep, 2017 as a visiting scholar. Zhongshan’s research interest mainly focus on identification of pathogenic genetic mutations for human neuropsychiatric disorders using bioinformatics and statistics methods.


Tiffany Ke

Visiting student

Tiffany, Xinxin KE (柯欣欣) obtained her BS in Biological Science and Engineering from Fuzhou University in 2014. She is currently a PhD student in School of Life Sciences, The Chinese University of Hong Kong. She joined the lab in Oct, 2017 as a visiting student. She is interested in the analysis, visualization and integration of multi-omics data obtained from microbial ecosystem using bioinformatics and computational skills



Yubin Xie 

Research Assistant

Yubin Xie was a research assistant in the lab from October, 2016 to June, 2017. He is now a PhD student at Tri-Institutional PhD Program in Computational Biology & Medicine.